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Can ACE inhibitors lower heart rate? ACE inhibitors (angiotensin converting enzyme inhibitors) work by preventing a natural body substance called angiotensin I from converting into angiotensin II, which cases blood vessels to narrow and constrict. This helps reduce the heart rate and lower blood pressure.
What time of day should ACE inhibitors be taken? When to take medicine: Take at least one blood pressure-lowering medication at bedtime. Drugs called ACE inhibitors and ARBs are the most effective when taken at this time. Here's why: Non-dipping is a major risk factor for stroke, heart attack and kidney disease.
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