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When should you take methotrexate? Most arthritis patients take methotrexate orally, in a dose consisting of several pills. Some find that splitting the dose eases GI side effects; take half the pills in the morning and the other half 12 hours later, preferably with food. Ask about medication.
Can sulfasalazine stop working? Sulfasalazine does not work straight away. Improvement in symptoms occurs gradually from about 6 to 12 weeks after commencing treatment.
How long does it take for sulfasalazine to work? Like all DMARDs, sulfasalazine takes time to work. Most patients start to feel the positive effects of at 4-8 weeks, with maximum benefit at 3-6 months.
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